retroviruses

ssRNA (+) type : messenger RNA

reverse transcriptase (RNA dependent DNA polymerase)

makes a DNA copy using an RNA template

phospholipid bilayer envelope with glycoprotein integral membrane proteins

from plasma membrane of host cell

Infects Helper T cells and neurons

affects immune system and brain

 

Replication of retroviruses

DNA copy of retrovirus genetic material is incorporated into genome of host cell.

anti-HIV drugs attempt to block different steps in virus replication and maturation

Why does HIV infections compromise the immune system?