Effect of environment of enzyme activity

Neither the extracellular nor the intracellular environment of cells is uniform throughout. For instance, consider an intestine epithelial cell in which the extracellular environment changes with the state of digestion. In addition, the intracellular space is compartmentallized by the various membranes that are found in the cell. Not only can the pH of various parts of the intracellular environment be different, but the concentration of various salts, substrates and inhibitors can also be different and change. To function in a highly regulated manner the activites of the enzymes that carry out the work of the cell are controlled by their environments. Thus factors like pH, salt concentration, substrate and inhibitor concentrations have profound effects of enzyme activity.

We will consider the effect of


salt, and


on the activities of enzymes

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