The electron transport chain of mitocondria is a series of coupled oxidation-reduction reactions.
The enzymes of the oxidation-reduction reactions are located, for the most part, in the inner mitochondrial membrane.
The free energy released in the coupled oxidation reduction reactions of the electron transport chain can be used to translocate protons from the matrix area, across the inner mitochondrial membrane and into the intermembrane space.
The proton concentration gradient across the inner mitochondrial membrane forms an electrochemical gradient (a gradient of protons and a potential difference across the inner membrane). The protons are able to pass down this gradient by using the integral membrane protein complex called the FoF1 complex. This process was named chemiosmosis by Roberts.
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