There are many differet enzymes in lysosomes. However they all function best in an acidic pH (5.0). In the table below some of the enzymes and catagories of enzyme are listed.
enzymes |
normal substrate |
disease of |
DNase and RNase |
RNA and DNA |
|
many different acid proteases |
proteins |
` |
polysaccharide and mucopolysaccharide degrading enzymes |
disaccharides, polysaccharides, glycolipids, glycoproteins, mucopolysaccharides |
Krabbe's disease (beta galactosidase deficient) Pompe's diseaase (alpha glucosidase deficient) Wollman's disease (acid lipase deficient) |
lipid degrading enzymes |
fatty acid esters, phospholipids |
Tay-Sach's disease (hexoseaminidase A deficient) Farber's disease (ceramidase deficient) |