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Leonard and Claire Tow Professor Inorganic Chemistry Sub-discipline Chair of the Ph.D. Program The Graduate Center of The City University of New York Telephone: 1-718-951-5000 Ext. 2827 (office) Ext. 5748 or 18900 (Lab) Email address: Rsdelgado@brooklyn.cuny.edu Education: Postdoctoral research associate (with Prof. John A. Osborn) at Louis Pasteur University Strasbourg, France (1976-1977) (Chemistry of zirconium hydrides and alkyls). Career: Brooklyn College CUNY, Associate Professor of Chemistry since 2004. Chemistry Center of the Venezuelan Institute for Scientific Research (IVIC), Caracas, Assistant Professor (1977-85), Associate Professor (1985-1988) and Full Professor (1989-2004). Visiting Professor at the Universities of Ulm, Zaragoza, Seville, Berkeley, Columbia, International Center for Science and Technology, Trieste, Institute of Catalysis CNRS in Lyon and Natural Museum of Natural History, Paris. Member of the Special Commission (UNSCOM) of the United Nations for the elimination of weapons of mass destruction of Iraq (1991-99). Research interests: Dr. Sanchez-Delgado has published over 110 articles in major journals, 4 patents and one book. His work is concerned with the synthesis of transition metal complexes and materials and their application to catalysis and medicinal chemistry. He has extensively studied the catalytic hydrogenation of aldehydes, ketones, and N- and S-heteroaromatic compounds using Ru, Rh, and Ir complexes of phosphine ligands, including liquid biphasic systems that have been patented; he also developed organometallic models of surface species and reactions relevant to hydrodesulfurization (HDS) and hydrodenitrogenation (HDN), two processes of great interest for the petroleum refining industry. Sanchez-Delgado and his coworkers also discovered a series of ruthenium compounds containing azole ligands that are active against Chagas disease and cancer, and successfully extended this idea to ruthenium and gold complexes of chloroquine as promising novel antimalarial agents. Current research projects: * The development of high-performance catalysts derived from transition metal complexes or nano-particles (Ru, Rh, Ir, Pd) for hydrogenation and carbonylation reactions related to the production of cleaner fossil fuels or the synthesis of pharmaceutical intermediates in homogeneous, heterogeneous or biphasic media. * The discovery of novel metal-based drugs against parasitic diseases (malaria, Chagas) and cancer, through the synthesis of new metal (Ru, Pd, Au) derivatives of N-donor ligands, the evaluation of their biological activity, and the study of their mechanisms of action. Awards: *Manuel Noriega Morales Award in Physical Sciences from the Organization of American States (1987); *Lorenzo Mendoza Fleury Award in Science from the Polar Foundation, Caracas (1989); *John Simon Guggenheim Fellow (1989); *Venezuelan National Prize in Science (1999). *Member of the Venezuelan Academy of Sciences and of the Latin American Academy of Science.
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