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Professor Inorganic Chemistry Sub-discipline Chair of the Ph.D. Program The Telephone: 1-718-951-5000 Ext. 2827 (office) Ext. 5748 or 18900 (Lab) Email address: Rsdelgado@brooklyn.cuny.edu
Postdoctoral research associate (with Prof. John A. Osborn) at Louis Pasteur University Strasbourg, France (1976-1977) (Chemistry of zirconium hydrides and alkyls). Career: Brooklyn College CUNY, Associate Professor 2004-2008; Professor 2008-present. Chemistry Center of the Venezuelan Institute for Scientific Research (IVIC), Caracas, Assistant Professor (1977-85), Associate Professor (1985-1988) and Full Professor (1989-2004). Visiting Professor at the Universities of Ulm, Zaragoza, Seville, Berkeley, Columbia, International Center for Science and Technology, Trieste, Institute of Catalysis CNRS in Lyon and Natural Museum of Natural History, Paris. Member of the Special Commission (UNSCOM) of the United Nations for the
elimination of weapons of mass destruction of Research interests: Dr.
Sanchez-Delgado has published 120 articles in major journals, 4 patents and
one book. His work is concerned with the synthesis of transition metal
complexes and materials and their application to catalysis and medicinal
chemistry. He has extensively studied the catalytic hydrogenation of
aldehydes, ketones, and N- and S-heteroaromatic compounds using Ru, Rh, and
Ir complexes; he also developed organometallic models of surface species and
reactions relevant to hydrodesulfurization (HDS) and hydrodenitrogenation
(HDN), two processes of great interest for the petroleum refining industry. Recently
this work was extended to nanostructured solid catalytic materials for
hydrogenation of aromatics and for transesterification of vegetable oils. Sanchez-Delgado
and his coworkers also discovered a series of ruthenium compounds containing
azole ligands that are active against Chagas disease and cancer, as well as
ruthenium and gold complexes of chloroquine as novel antimalarial and
antitumor agents. The mechanisms of biological action of these organometallic
compounds has been elucidated by use of a variety of physical and biochemical
techniques. Current research projects: *The development of high-performance catalysts derived from transition metal complexes or nanostructured materials (Ru, Rh, Ir, Pd) for hydrogenation reactions related to the production of cleaner fossil fuels or the synthesis and stabilization of biodiesel.* The discovery of novel metal-based drugs against parasitic diseases (malaria, Chagas) and cancer, through the synthesis of new metal (Ru, Pd, Au) derivatives of N-donor ligands, the evaluation of their biological activity, and the study of their mechanisms of action. Awards: *Leonard and Claire Tow Professor 2007-2009 at Brooklyn College CUNY. *Manuel Noriega Morales Award in Physical Sciences from the Organization of American States (1987); *Lorenzo Mendoza Fleury Award in Science from the Polar Foundation, *John Simon Guggenheim Fellow (1989); *Venezuelan National Prize in Science (1999). *Member of the
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