Recent Publications
Past Publications
Marcinkeviciene J.A., Magliozzo R.S, Blanchard J.S.
Protein Purification and characterization of the Mycobacterium
smegmatis catalase-peroxidase involved in isoniazid activation. J.
Biol. Chem. 1995 Sep 22;270(38):22290-5.
Zhao, X.; Yu, H.; Yu, S.; Wang, F.; Sacchettini, J. C.; Magliozzo, R. S.
Hydrogen Peroxide-Mediated Isoniazid Activation Catalyzed by Mycobacterium tuberculosis Catalase-Peroxidase (KatG) and Its S315T Mutant
Biochemistry; (Article); 2006; ASAP Article; DOI: 10.1021/bi051967o
[Abstract]
[Full
Text] [PDF]
Kapetanaki SM, Chouchane S, Yu S, Magliozzo RS, Schelvis JP.
Resonance Raman spectroscopy of Compound II and its decay in Mycobacterium tuberculosis catalase-peroxidase KatG and its isoniazid resistant mutant S315T.
J Inorg Biochem. 2005 Jun;99(6):1401-6.
[Abstract]
[Full
Text] [PDF]
Kapetanaki SM, Chouchane S, Yu S, Zhao X, Magliozzo RS, Schelvis JP.
Mycobacterium tuberculosis KatG(S315T) catalase-peroxidase retains all active site properties for proper catalytic function.
Biochemistry. 2005 Jan 11;44(1):243-52.
[Abstract]
[Full
Text] [PDF]
Zhao X, Girotto S, Yu S, Magliozzo RS.
Evidence for radical formation at Tyr-353 in Mycobacterium tuberculosis catalase-peroxidase (KatG).
J Biol Chem. 2004 Feb 27;279(9):7606-12. Epub 2003 Dec 9.
[Abstract]
[Full
Text] [PDF]
Shengwei Yu, Stefania Girotto,
Chiuhong Lee, and Richard S.
Magliozzo,
Reduced Affinity for Isoniazid in
the S315T Mutant of Mycobacterium tuberculosis KatG Is a Key Factor
in Antibiotic Resistance
J. Biol. Chem.,
Apr 2003; 278: 14769 - 14775.
[Abstract]
[Full
Text] [PDF]
Salem Chouchane, Stefania Girotto, Sofia
Kapetanaki, Johannes P. M. Schelvis, Shengwei Yu, and Richard S.
Magliozzo,
Analysis of Heme Structural
Heterogeneity in Mycobacterium tuberculosis Catalase-Peroxidase (KatG)
J. Biol. Chem., Feb 2003; 278: 8154 - 8162.
[Abstract]
[Full
Text] [PDF]
Salem Chouchane, Stefania Girotto, Shengwei
Yu, and Richard S.
Magliozzo
Identification and
Characterization of Tyrosyl Radical Formation in Mycobacterium
tuberculosis Catalase-Peroxidase (KatG)
J. Biol. Chem., Nov 2002; 277: 42633 - 42638.
[Abstract]
[Full
Text] [PDF]
Salem
Chouchane, Istvan Lippai, and Richard S. Magliozzo*;
Catalase-Peroxidase (Mycobacterium tuberculosis KatG) Catalysis and
Isoniazid Activation, Biochemistry; 2000; 9975-9983.
Tian Y, Xing Y, Magliozzo R.S, Yu K, Bloom B.R, Chan J. A commercial
preparation of catalase inhibits nitric oxide production by activated murine
macrophages: role of arginase. Infect. Immun. 2000
May;68(5):3015-8.
István Lippai, Richard S. Magliozzo, and Jack Peisach*
; EPR Spectroscopic Reinvestigation of the Activation of Iron Complexes
of PMAH as a Bleomycin Model, Journal of the American Chemical
Society; 1999; 121(4);780-784.
Way S.S, Sallustio S, Magliozzo R.S, Goldberg M.B. Impact of either
elevated or decreased levels of cytochrome bd expression on Shigella
flexneri virulence. J. Bacteriol. 1999; 181(4):1229-37.
Yu K, Mitchell C, Xing Y, Magliozzo R.S., Bloom B.R, Chan J. Toxicity
of nitrogen oxides and related oxidants on mycobacteria: M. tuberculosis is
resistant to peroxynitrite anion. Tuber Lung Dis. 1999;79(4):191-8.
Reddy S.G, Wong K.K, Parast C.V, Peisach J, Magliozzo R.S, Kozarich J.W.
Dioxygen inactivation of pyruvate formate-lyase: EPR evidence for the
formation of protein-based sulfinyl and peroxyl radicals.
Biochemistry. 1998 13;37(2):558-63.
Richard S. Magliozzo* and Jovita A. Marcinkeviciene
; Evidence for Isoniazid Oxidation by Oxyferrous Mycobacterial
Catalase-Peroxidase, Journal of the American Chemical Society;1996;
11303-11304.
