Zhen Huang's Laboratory


Prof. Huang
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Selenium Derivatization of DNA/RNA for X-ray Crystallography

                                    Crystal Structure.jpg (162305 bytes)

X-ray crystal structure (1.3 resolution) of the decamer DNA duplex [d(GCGTAUSe-MeACGC)] superimposed on experimental electron density based on MAD phases (two selenium atoms per asymmetric unit, pink). Biochimie, 2002, 84, 849-858.


                        crystal diff white.jpg (137122 bytes)

Data of glucose isomerase with 1.4 resolution (practice) was collected at Brookhaven National Laboratory in 2003.


RNA Artwork:  

         atp2.gif (15788 bytes)                                                      hamm4.gif (5404 bytes)

      A Person Thinking                                           A Couple Dancing



Contact:       Prof. Zhen Huang

Program of Chemistry and Biochemistry

Department of Chemistry,

Brooklyn College

The City University of New York

2900 Bedford Avenue

Brooklyn, New York 11210



E-MAIL:     zhuang@brooklyn.cuny.edu  

PHONE:    (718) 951-5746    

FAX:         (718) 951-4607