n Doubters 
  - No therapeutic purpose
  - Not life threatening
  - Sensitivity and specificity of PSA
n Supporters of screening for men
    of African descent
  - High incidence rate
  - bcl-2 gene responsible for rapid
       tumor growth in
  - Revised PSA reference values for
       in men of African descent 
    Detect 95% of the prostate cancer
    Reduced risk of 
      False positives
      False negatives