n Antiandrogen
  - Prevent flare 
  - Cause
    Nausea
    Vomiting
    Diarrhea
    Breast growth/tenderness 
n Ketoconazole 
  - Liver problems
n Aminoglutethimide
  - Skin rashes
n Total androgen blockade
  - More side effects
n Weakening of bones in older men